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Controlled Release in Oral Drug Deliveryprovides focus on specific topics, complementing other books in the initial CRS series. Each chaptersets the context for the inventions described and describe the latitude that the inventions allow. In order to provide some similar look to each chapter, the coverage includes the historical overview, candidate drugs, factors influencing design and development, formulation and manufacturing and delivery system design. This volumewas written along three main sections: the relevant anatomy and physiology, a discussion on candidates for oral drug delivery and the major three groups of controlled release systems: diffusion control (swelling and inert matrices); environmental control (pH sensitive coatings, time control, enzymatic control, pressure control) and finally lipidic systems.

bioavailability Control Release dosage form drug delivery enteric coating excipients hydrophilic hydroxypropyl methylcellulose hypromellose ibuprofen lipid matrix polymer small intestine